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Gavin Sherlock

Academic Appointments

  • Associate Professor of Genetics

Key Documents

Contact Information

  • Academic Offices
    Personal Information
    Email

Bio

Academic Appointments

Honors and Awards

  • Army Breast Cancer Research Fellowship, Department of Defence (1997-1998)
  • Cold Spring Harbor Fellowship, Cold Spring Harbor Laboratory (1996-1997)
  • Prize Studentship, The Wellcome Trust (1991-1994)
  • John Buckley Entrance Scholarship for Science, Manchester University (1988-1991)

Professional Education

B.Sc.: Manchester University, Genetics (1991)
Ph.D.: Manchester University, Molecular Biology (1994)

Research & Scholarship

Current Research and Scholarly Interests

1. Evolution and the Adaptive Landscape

When yeast are evolved under various selective pressures in a chemostat, mutations that arise and provide an adaptive advantage will expand within the population. We are using high throughput sequencing to determine the identity of such mutations, as well as to understand the dynamics of the mutations within the populations, and the interactions between the mutations (such as epistasis).

2. Genome Annotation by Transcriptome Sequencing

The set of genes in a sequenced genome has typically been defined using various prediction criteria (such as ORFs capable of encoding a protein > 100 amino acids), coupled with experimental data, such as transposon mutagenesis and EST sequencing. The availability of high throughput sequencing now allows full transcriptome sequencing to better annotate the transcribed regions of the genome, and we are applying this to various yeasts.

Teaching

Courses

2013-14

Prior Year Coursescourses of Gavin Sherlock

Postdoctoral Advisees

Dimitra AngeliLucas Herissant

Graduate and Fellowship Program Affiliations

Publications

Publications

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