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Garry Nolan

Academic Appointments

  • Rachford and Carlota Harris Professor

Contact Information

  • Academic Offices
    Personal Information
    Email Tel (650) 725-7002
    Alternate Contact
    Howard Guss Administrative Associate / Office Manager Tel Work 650-725-7002

Bio

Administrative Appointments

  • NCI-Frederick Advisory Committee, NCI (2011 - 2015)
  • Board of External Experts, National Heart, Lung, and Blood Institute of the NIH (2007 - present)
  • Director, Stanford NHLBI Proteomics Center, National Heart, Lung, and Blood Institute of the NIH (2010 - 2015)

Honors and Awards

  • Teal Innovator Award, Department of Defense (2012-2017)
  • Outstanding Research Achievement, for Mass Cytometry and CyTOF, Nature Publishing Group (2011)
  • Stohlman Scholar, Leukemia and Lymphoma Society (2000)
  • Scholar of the Leukemia Society, Leukemia and Lymphoma Society (1996-2000)
  • Burrough's Wellcome Investigator's Award In Pharmacology, Burroughs Wellcome (1995-2000)

Professional Education

Postdoctoral Fellowship: MIT, David Baltimore Laboratory, Biochemistry (1993)
Ph.D.: Stanford University, Genetics (1989)
B.S.: Cornell University, Genetics (1983)

Research & Scholarship

Current Research and Scholarly Interests

Our areas of expertise include signal transduction, immunology, cancer biology, auto-immunity, retroviral design, bioinformatics and genetics. Our laboratory’s recent interests include studying signaling alterations at the single cell level in leukemia and lymphomas, cancer stem cells, and determining which of these signaling attributes correlate with patient outcome, drug reactivity and mechanism of disease progressions.

We recently developed for immunology studies CyTOF, an advanced flow cytometric tool that is a hybrid flow cytometer-mass spectrometer instrument. This tool has revolutionized single cell analysis by enabling direct measurement of up to 100 parameters per cell. With novel computational approaches we expect this number to reach 500 or more parameters per cell--- at the rate of thousands of cells per second. This "depp phenotypic profiling" is allowing an entirely new way of looking at the immune system and cancer.

The lab puts substantial effort into bioinformatics approaches to mine the datasets we collect and to automate the production of network models of the signaling pathways affected. For this, we have collaborations with statisticians, engineering departments, and computer design specialists here at Stanford and UC Berkeley to extend our efforts to make the program in the laboratory extremely cross-disciplinary.

Dr. Nolan has published over 170 papers, most in top tier journals, has over 20 issued patents, has been cited as one of the top inventors at Stanford, and has a strong record of translating technology and inventions for the public good. Dr. Nolan was recently awarded the Department of Defense Teal Innovator Award for work on ovarian cancer. The journal Nature awarded the “Outstanding Research Achievement for 2011” to the Nolan Lab for its work in single-cell analysis by mass cytometry.

Teaching

Courses

2014-15

Prior Year Coursescourses of Garry Nolan

Publications

Publications

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Publication Topics

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