Cancer Institute A national cancer institute
designated cancer center
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Lawrence Leung

Academic Appointments

  • Maureen Lyles D'Ambrogio Professor in the School of Medicine

Key Documents

Contact Information

  • Clinical Offices
    Hematology Clinic 875 Blake Wilbur Dr Clinic C MC 5820 Stanford, CA 94305
    Tel Work (650) 498-6000 Fax (650) 724-5203
    Hematology Clinic 875 Blake Wilbur Dr Clinic C MC 5820 Stanford, CA 94305
    Tel Work (650) 498-6000 Fax (650) 724-5203
  • Academic Offices
    Personal Information
    Email Tel (650) 725-4036
    Not for medical emergencies or patient use


Clinical Focus

  • Cancer> Hematology
  • Hematology

Academic Appointments

Administrative Appointments

  • Chief of Staff, VA Palo Alto Health Care System (2006 - present)
  • Senior Associate Dean for Veterans Affairs, School of Medicine (2006 - present)

Professional Education

Fellowship: New York Hospital NY (1981)
Internship: New York Hospital NY (1976)
Medical Education: Columbia University NY (1975)
Residency: New York Hospital NY (1978)
Board Certification: Hematology, American Board of Internal Medicine (1980)
Board Certification: Internal Medicine, American Board of Internal Medicine (1978)
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Research & Scholarship

Current Research and Scholarly Interests

Our long-term interest is to have a better understanding of the natural antithrombotic pathways and the pathophysiology of vascular thrombosis. We have focused on thrombin, the key enzyme in the blood clotting cascade. Using a library of thrombin mutants generated by site-directed mutagenesis, we have mapped the critical functional sites on thrombin for its interactions with its diverse substrates. We are studying a thrombin-activatable carboxypeptidase that plays a key role in the physiologic regulation of thrombinÂ’'s pro-thrombotic and pro-inflammatory properties. Our goal is to develop new antithrombotic agents and devise new diagnostic tests for vascular thrombotic disorders.




Postdoctoral Advisees

Shwu Shin ChangXiaomei Ge



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Publication Topics

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