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John P.A. Ioannidis

Academic Appointments

  • C. F. Rehnborg Professor in Disease Prevention in the School of Medicine and Professor of Health Research and Policy and, by courtesy, of Statistics

Key Documents

Contact Information

  • Academic Offices
    Personal Information
    Email Tel (650) 725-5465
    Alternate Contact
    Tamica Garner Assistant to the Director Tel Work 650-7255465


John P.A. Ioannidis holds the C.F. Rehnborg Chair in Disease Prevention at Stanford University and is Professor of Medicine, Professor of Health Research and Policy, and Director of the Stanford Prevention Research Center (SPRC) at Stanford University School of Medicine, Professor of Statistics (by courtesy) at Stanford University School of Humanities and Sciences, one of the two Directors of the Meta-Research Innovation Center at Stanford (METRICS), member of the Stanford Cancer Institute and the Stanford Cardiovascular Institute, and affiliate in the Stanford Center on Longevity and the Woods Institute for the Environment.

He was born in New York, NY in 1965 and grew up in Athens, Greece. He was Valedictorian of his class (1984) at Athens College and won a number of early awards, including the National Award of the Greek Mathematical Society in 1984. He graduated in the top rank of his class from the School of Medicine, University of Athens, in 1990 and received also a doctorate in biopathology from the same institution. He trained at Harvard and Tufts, specializing in Internal Medicine and Infectious Diseases, and then held positions at NIH, Johns Hopkins and Tufts before returning to Greece in 1999. From 1999 until 2010 he chaired the Department of Hygiene and Epidemiology at the School of Medicine, University of Ioannina in Greece, as a tenured professor since 2003. He has been adjunct faculty for the Tufts University School of Medicine since 1996, with the rank of professor since 2002. In 2008-2010 he led the Genetics/Genomics component of the Tufts Clinical and Translational Science Institute (CTSI) and the Center for Genetic Epidemiology and Modeling (CGEM) of the Tufts Institute for Clinical Research and Health Policy Studies at Tufts Medical Center. He is also adjunct professor of epidemiology at the Harvard School of Public Health and visiting professor of epidemiology and biostatistics at Imperial College London.

Dr. Ioannidis is a member of the executive board of the Human Genome Epidemiology Network, and senior advisor on knowledge integration at NCI, and has served as President of the Society for Research Synthesis Methodology, as member of the editorial boards of leading international journals (including PLoS Medicine, Lancet, Annals of Internal Medicine, JNCI, Science Translational Medicine, Molecular and Cellular Proteomics, Clinical Chemistry, AIDS, International Journal of Epidemiology, Journal of Clinical Epidemiology, Clinical Trials, Cancer Treatment Reviews, and PLoS ONE, among others) and as Editor-in-Chief of the European Journal of Clinical Investigation. He has given more than 300 invited and honorary lectures. He is one of the most-cited scientists worldwide, with indices Hirsch h=119, Hirsch m=6.0, and Schreiber hm=70 per GoogleScholar as of 8/2014 (h=97 per ISI). He has received several awards, including the European Award for Excellence in Clinical Science for 2007, and has been inducted in the Association of American Physicians in 2009 and in the European Academy of Cancer Sciences in 2010. The PLoS Medicine paper on “Why most Published Research Findings are False,” has been the most-accessed article in the history of Public Library of Science (over 1 million hits). The Atlantic selected Ioannidis as the Brave Thinker scientist for 2010 claiming that he “may be one of the most influential scientists alive”. His book Toccata for the Girl with the Burnt Face (Kedros 2012, in Greek) was shortlisted for the best book Anagnostis awards in Greece in 2013 and his latest book, Variations on the Art of the Fugue and a Desperate Ricercar (Kedros, July 2014, in Greek), has already been well received. He considers himself privileged to have learnt and to continue to learn from interactions with students and young scientists (of all ages) from all over the world and to be constantly reminded that he knows next to nothing.

Administrative Appointments

  • C.F. Rehnborg Professor in Disease Prevention and Director, Stanford Prevention Research Center (2010 - present)
  • Co-Director, Meta-Research Innovation Center at Stanford (METRICS) (2013 - present)
  • Professor of Medicine, Stanford University School of Medicine (2010 - present)
  • Professor of Health Research and Policy, Stanford University School of Medicine (2011 - present)
  • Professor of Statistics (by courtesy), Stanford University School of Humanities and Sciences (2011 - present)
  • Affiliated faculty, Woods Institute for the Environment (2011 - present)
View All 14administrative appointments of John Ioannidis

Honors and Awards

  • European Award for Excellence in Clinical Science, European Society for Clinical Investigation (2007)
  • Executive board member and center director, Human Genome Epidemiology Network (2004-)
  • President, Society for Research Synthesis Methodology (2009-2010)
  • Elected member, Association of American Physicians (2009-)
  • Elected fellow, European Academy of Cancer Sciences (2010-)

Professional Education

Fellowship: New England Medical Center, Tufts University School of Medicine, Infectious Diseases (1996)
Residency: New England Deaconess Hospital, Harvard Medical School, Internal Medicine (1993)
DSc: University of Athens School of Medicine, Athens, Greece, Biopathology (1996)
MD: University of Athens School of Medicine, Athens, Greece, Medicine (1990)

Research & Scholarship

Current Research and Scholarly Interests

I have worked in the fields of evidence-based medicine, clinical investigation, clinical and molecular epidemiology, clinical research methodology, empirical research methods, statistics, and genomics. I have a strong interest in large-scale evidence (in particular randomized trials and meta-analyses) and in appraisal and control of diverse biases in biomedical research. I am interested in developing and applying new research methods, and in the interdisciplinary enhancement of existing research methods for study design and analysis in biomedicine. Some of my most influential papers in terms of citations are those addressing issues of replication validity of genetic association studies, biases in biomedical research, research synthesis methods, extensions of meta-analysis, genome-wide association studies and agnostic evaluation of associations, and validity of randomized trials and observational research. I have also designed, steered and participated in influential randomized trials (in particular, the major trials that changed decisively the management and outcome of HIV infection, but also trials in nephrology, and in antibiotic use in the community), and large international consortia that have helped transform the efficiency of research in diverse fields of genomic, molecular and clinical epidemiology. I enjoy working with a diverse array of colleagues from very diverse disciplines and to have an opportunity to learn from both senior and junior investigators, and particularly students at all levels.

Clinical Trials




Prior Year Coursescourses of John Ioannidis

Postdoctoral Advisees

Shanil EbrahimEwoud Schuit



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