Ashby Morrison
Academic Appointments
- Assistant Professor, Biology (School of Humanities and Sciences)
- Member, Stanford Cancer Institute
Key Documents
Contact Information
- Academic Offices
Personal Information Email Tel (650) 721-6589Alternate Contact Elyse Pierson Administrative Assistant Email
Professional Overview
Honors and Awards
- Pathways to Independence Award (K99/R00), NIH (2009-2012)
Graduate & Fellowship Program Affiliations
Internet Links
Scientific Focus
Current Research Interests
Our research interests are to elucidate the contribution of chromatin to mechanisms that promote genomic integrity. The regulation of chromatin is a crucial component of DNA metabolism and processing in eukaryotic organisms. Chromatin-remodeling complexes, modified histones, and higher order chromatin structure are all factors influencing genome stability. We utilize an integrated approach of genetic, biochemical, and molecular techniques, in both yeast and mammalian systems, to examine the involvement of chromatin in processes that prevent genome instability and the pathogenesis of disease.
Publications
- New marks on the block: Set5 methylates H4 lysines 5, 8 and 12. Nucleus. 2012; (4): 335-9
- Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes. Nat Rev Mol Cell Biol. 2009; (6): 373-84
- Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell. 2007; (3): 499-511
- INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell. 2004; (6): 767-75
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