Cancer Institute A national cancer institute
designated cancer center
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Ashley Zehnder

Academic Appointments

  • Postdoctoral Research fellow, Program in Epithelial Biology
  • Ph.D. Student in Cancer Biology, admitted Autumn 2009

Key Documents

Contact Information

  • Academic Offices
    Personal Information


Professional Education

Doctor of Veterinary Medicine: University of Florida, Veterinary Medicine (2005)
Internship: Animal Medical Center, New York, Small Animal Medicine (2006)
Residency: Univ. of California, Davis, Companion Exotics (2009)
Dipl ABVP: American Board of Veterinary Practitioners, Avian Medicine (2009)

Research & Scholarship

Current Research and Scholarly Interests

My current research focuses on novel methods to Erk1/2 MAP kinase (MAPK) cascade in cancer. Up-regulation occurs in >30% of human cancers, making this a key therapeutic target. MAPK scaffolds, such as IQGAP1, assemble pathway kinases together to effect signal transmission. Disrupting scaffold function offers a potentially orthogonal approach to MAPK cascade inhibition. We have IQGAP1 to be necessary for Ras-driven tumorigenesis and are utilizing this discovery to dissect the ERK1/2 pathway.

Lab Affiliations



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Publication Topics

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