Cancer Institute A national cancer institute
designated cancer center
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Joshua Elias

Academic Appointments

  • Assistant Professor of Chemical and Systems Biology

Key Documents

Contact Information

  • Academic Offices
    Personal Information
    Email
    Administrative Contact
    Sarah Alexander Administrative Assistant Tel Work 650-724-2971

Bio

Academic Appointments

Honors and Awards

  • Medical Research Program, W. M. Keck Foundation (7/1/2013 - 6/30/2016)
  • Innovation Award, Damon Runyon Cancer Research Foundation (1/1/11-12/31/13)

Professional Education

Ph.D.: Harvard University, Cell Biology (2006)
B.S.: Cornell University, Biology, Genetics (1998)

Research & Scholarship

Current Research and Scholarly Interests

The Elias Lab seeks to develop and apply methods for large scale proteome characterization to solve fundamental problems in cell biology and disease. The growing field of proteomics has the lofty goal of characterizing the proteins in any isolated complex, subcellular compartment, cultured cell line or tissue. We use mass spectrometry-based approaches which can do more than simply determining the identity of a protein isolated in a polyacrylamide gel -- rapidly advancing technologies are allowing us to measure dynamic changes in protein abundances, post-translational modification states, splice isoforms, interaction partners, and localization across multiple cell states. The combination of liquid chromatography with tandem mass spectrometry (LC-MS/MS) has emerged as the most robust technology for making proteome-scale discoveries. Although the tools of proteomics have greatly advanced in recent years, many challenges lie ahead. Our lab focuses on developing new methods in protein fractionation, instrumentation, and data analysis to meet these challenges, and then applies them to studying important biomedical paradigms, including cancer, aging, and stem cell biology.

Teaching

Courses

2013-14

Prior Year Coursescourses of Joshua Elias

Postdoctoral Advisees

Niclas Olsson

Graduate and Fellowship Program Affiliations

Publications

Publications

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Publication Topics

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