Quynh-Thu Le
Academic Appointments
- Professor - Med Center Line, Radiation Oncology - Radiation Therapy
- Professor - Med Center Line (By courtesy), Otolaryngology (Head and Neck Surgery)
- Member, Bio-X
- Member, Cancer Center
Contact Information
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Clinical Offices
Radiation Therapy 875 Blake Wilbur Dr Clinic D Stanford, CA 94305-5847 Tel Work (650) 723-6171 Fax (650) 725-8231Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
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Academic Offices
Administrative Contact Trevor Elizabeth Krakow Research Assistance Email Tel Work 725-4777Not for medical emergencies or patient use
Professional Snapshot
Clinical Focus
- Cancer > Head and Neck Cancer
- Cancer > Radiation Oncology
- Head and Neck Cancers
- Head and Neck Cancers - Radiation Oncology
- Larynx Cancer
Administrative Appointments
- Editorial Board, Journal of Clinical Oncology (2005 - 2009)
- IMRT Practicum Course Co-Director, American Society of Therapeutic Oncology and Radiology (2004 - 2009)
- Educational Committee Vice Chair, American Society of Therapeutic Radiology and Oncology (2005 - present)
- Director of Clinial research, Department of radiation oncology, stanford university (2005 - present)
- Editorial Board, Int J Radiation Oncology Biology Physics (2003 - present)
Professional Education
| Board Certification: | Radiation Oncology, American Board of Radiology (1998) |
| Residency: | UCSF Medical Center, CA (1997) |
| Internship: | Highland General Hospital, CA (1994) |
| Medical Education: | UCSF School of Medicine, CA (1993) |
| MD: | UCSF, Medicine (1993) |
Postdoctoral Advisees
Graduate & Fellowship Program Affiliations
Scientific Focus
Research Interests
My laboratory research interest focusses on the identification of serum markers for tumor hypoxia and for prognosis in patients with head and neck or lung cancers. I am also conducting a number of clinical trials specifically in patients with these tumors. For head and neck cancer, I am conducting a trial using iressa, chemotherapy and re-irradiation in patients with unresectable recurrent tumors, a trial using Evoxac to improve radiation-induced xerostomia in previously treated patients, and 2 trials on serum markers for hypoxia and treatment outcomes. For lung cancer patients, I am conducting a phase II trial with Tirapazamine and conventional treatment in patients with limited stage small cell lung cancers through the Southwest Oncology Group and a trial on using stereotactic radiosurgical ablation for small unresectable or metastatic lung tumors.
Clinical Trials
- Chemotherapy and Radiation Therapy With or Without Vandetanib in Treating Patients With High-Risk Stage III or Stage IV Head and Neck Cancer Recruiting
- Identification and Characterization of Novel Proteins in Head and Neck Cancer Recruiting
- Identification of Secreted Markers for Tumor Hypoxia in Patients with Head and Neck or Lung Cancers Recruiting
- Phase II Lapatinib and Radiation for Stage III-IV Head and Neck Cancer Patients Who Cannot Tolerate Concurrent Chemotherapy Recruiting
- Real-Time kV Imaging vs. Real-Time 3D Patient Surface Tracking for Head & Neck Cancer Recruiting
Publications
- Integrating biologically targeted therapy in head and neck squamous cell carcinomas. Semin Radiat Oncol. 2009; (1): 53-62
- Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell. 2009; (1): 35-44
- X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas. Transl Oncol. 2009; (1): 31-8
- Metabolic tumor volume predicts for recurrence and death in head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2009; (5): 1335-41
- Comparison of treatment results between adult and juvenile nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2009; (4): 1064-70
Trial Administration