Gestational Trophoblastic Disease Facts

There are two main types of gestational trophoblastic disease (GTD): Hydatidiform Mole and choriocarcinoma.

Hydatidiform Mole
Hydatidiform mole is the most common form of GTD, and occurs following fertilization when the placenta forms in the absence of a fetus, or with a partial and abnormal fetus. This is also called a molar "pregnancy," but it is not possible for a normal baby to form. Hydatidiform moles are not cancerous, but they may develop into cancerous GTDs.
Choriocarcinoma
Choriocarcinoma is a cancerous condition that most commonly occurs following a hydatidiform mole. It is much more rare, occurring in about 0.004% of all pregnancies.

Symptoms

Persistent irregular vaginal bleeding during early “pregnancy” or after the delivery of a baby

Age: Gestational trophoblastic disease occurs in women of childbearing age.
Prior molar pregnancy
Prior miscarriage(s) or problems getting pregnant
Blood type: Women with blood type A or AB are at slightly higher risk than those with type B or O.
Diet: A few studies have found that a low level of beta-carotene (a nutrient converted to vitamin A in the body) in the diet may be linked with a higher risk of complete molar pregnancies. More research is needed to confirm this.
Family history